At a glance
Research Projects to Enhance Applicability of Mammalian Models for Translational Research (R01 Clinical Trial Not Allowed) is a federal competitive grant from National Institutes of Health for the science & technology sector. Funding is up to $499K. Eligible applicants: Small businesses; Independent school districts; Private institutions of higher education; City or township governments; For profit organizations other than small businesses; Nonprofits that do not have a 501(c)(3) status. The application deadline is September 7, 2026. Apply via the official listing at www.grants.gov.
- Amount
- Up to $499K
- Deadline
- Sep 7, 2026
- Type
- Competitive
- Status
- Closing soon
About this program
Through this Notice of Funding Opportunity (NOFO), the National Cancer Institute (NCI) invites applications for projects to expand, improve, or transform the utility of mammalian cancer and tumor models for translational research. With this NOFO, the NCI intends to encourage submission of projects devoted to demonstrating that mammalian models or their derivatives used for translational research are robust representations of human biology, are appropriate to test questions of clinical importance, and provide reliable information for patients' benefit. These practical goals contrast with the goals of many mechanistic, NCI-supported R01 projects that employ mammals, or develop and use mammalian cancer models, transplantation tumor models, or models derived from mammalian or human tissues or cells for hypothesis-testing, non-clinical research. Among many other possible endeavors, applicants in response to this FOA could propose demonstrations of how to overcome translational deficiencies of mammalian oncology models, define new uses of mammalian models or their genetics for unexplored translational challenges, advance standard practices for use of translational models, test approaches to validate and credential models, or challenge current practices for how models are used translationally
Who can apply
Small businesses; Independent school districts; Private institutions of higher education; City or township governments; For profit organizations other than small businesses; Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education; Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education; Special district governments; Others (see text field entitled "Additional Information on Eligibility" for clarification); County governments; Native American tribal governments (Federally recognized); Public housing authorities/Indian housing authorities; State governments; Native American tribal organizations (other than Federally recognized tribal governments); Public and State controlled institutions of higher education. Other Eligible Applicants include the following: Alaska Native and Native Hawaiian Serving Institutions; Asian American Native American Pacific Islander Serving Institutions (AANAPISISs); Eligible Agencies of the Federal Government; Faith-based or Community-based Organizations; Hispanic-serving Institutions; Historically Black Colleges and Universities (HBCUs); Indian/Native American Tribal Governments (Other than Federally Recognized); Non-domestic (non-U.S.) Entities (Foreign Organizations); Regional Organizations; Tribally Controlled Colleges and Universities (TCCUs) ; U.S. Territory or Possession.
How to apply
Apply through Grants.gov using funding opportunity number PAR-24-306. Register your organization (SAM.gov + Grants.gov) before the deadline, then submit the application package listed in the official notice.
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