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Federal Forecasted GRANTS-GOV-359827

Notice of Intent to Publish a Funding Opportunity Announcement for ClinGen Genomic Curation Expert Panels

National Institutes of Health (NIH) · Competitive grant · Science & Technology

At a glance

Notice of Intent to Publish a Funding Opportunity Announcement for ClinGen Genomic Curation Expert Panels is a federal competitive grant from National Institutes of Health for the science & technology sector. Funding: 880000. Eligible applicants: Public and State controlled institutions of higher education; Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education; Small businesses; State governments; County governments; Nativ. Applications are accepted on a rolling basis. Apply via the official listing at www.grants.gov.

Amount
$880K total
Deadline
Rolling
Type
Competitive
Status
Forecasted

About this program

The Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD), with other NIH Institutes and Centers (ICs) - National Eye Institute, National Institute of Arthritis and Musculoskeletal and Skin Diseases, National Institute on Deafness and Other Communication Disorders, National Institute of Mental Health, National Institute of Neurological Disorders and Stroke, National Center for Advancing Translational Sciences, and National Cancer Institute - intends to publish a Notice of Funding Opportunity (NOFO) to solicit applications for the establishment and continuation of Genomic Curation Expert Panels that manually curate, review and define the clinical relevance of genes and variants as part of the NIH established and funded Clinical Genome Resource (ClinGen). Despite advances in genomic sequencing technology and increasing adoption in clinical practice, there are many genomic variants with unknown significance (VUS), and there is limited understanding of their function. This presents barriers to genomic and precision medicine. To address this need for better knowledge about the links between genes, variants, and disease, this NOFO will facilitate the development of Expert Panels to select genes and variants associated with diseases or conditions of high priority for participating NIH Institutes and Centers (ICs) and to systematically determine their clinical significance for diagnosis and treatment of these diseases or conditions. The Expert Panels funded through this NOFO are required to utilize the NHGRI ClinGen and the NCBI ClinVar procedures, interfaces, tools, and informatics infrastructure. Ultimately, these expert panels contribute to an authoritative, centralized, and public resource, through aggregation, evaluation, and sharing of expert-curated data about genetic conditions, and the variants that cause them.

Who can apply

Public and State controlled institutions of higher education; Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education; Small businesses; State governments; County governments; Native American tribal governments (Federally recognized); For profit organizations other than small businesses; Native American tribal organizations (other than Federally recognized tribal governments); Private institutions of higher education; Public housing authorities/Indian housing authorities; Independent school districts

How to apply

Apply through Grants.gov using funding opportunity number NOT-HD-25-006. Register your organization (SAM.gov + Grants.gov) before the deadline, then submit the application package listed in the official notice.

Apply at official source