At a glance
Discovery of in vivo Chemical Probes for the Nervous System (R01 Clinical Trial Not Allowed) is a federal competitive grant from National Institutes of Health for the science & technology sector. Eligible applicants: Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education; Small businesses; State governments; Special district governments; Native American tribal organizations (other than Federall. The application deadline is March 5, 2027. Apply via the official listing at www.grants.gov.
- Amount
- See listing
- Deadline
- Mar 5, 2027
- Type
- Competitive
- Status
- Open
About this program
The purpose of this Notice of Funding Opportunity (NOFO) is to support investigators who have the interest and capability to join efforts for the discovery of in vivo chemical probes for novel brain targets. It is expected that applicants will have, in hand, the starting compounds (validated hits) for chemical optimization and bioassays for testing new analog compounds.Through this NOFO, NIH wishes to stimulate research in:Discovery and development of novel, small molecules for their potential use in understanding biological processes relevant to the missions of National Institute of Mental Health (NIMH), National Institute on Drug Abuse (NIDA), National Eye Institute (NEI), and/or National Institute on Aging (NIA) andDiscovery and/or validation of novel, biological targets that will inform studies of brain disease mechanisms.Emphasis will be placed on projects that provide new insight into important disease-related biological targets and biological processes.
Who can apply
Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education; Small businesses; State governments; Special district governments; Native American tribal organizations (other than Federally recognized tribal governments); Independent school districts; For profit organizations other than small businesses; Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education; Private institutions of higher education; City or township governments; Public housing authorities/Indian housing authorities; County governments; Native American tribal governments (Federally recognized); Others (see text field entitled "Additional Information on Eligibility" for clarification); Public and State controlled institutions of higher education. Refer to Section III. Eligibility Information in the NOFO for additional information on eligibility.Foreign Organizations/International CollaborationsNon-domestic (non-U.S.) Entities (Foreign Organizations) are eligible to apply.Non-domestic (non-U.S.) components of U.S. Organizations are eligible to apply.Foreign components, as defined in the NIH Grants Policy Statement, are allowed.
How to apply
Apply through Grants.gov using funding opportunity number PAR-27-081. Register your organization (SAM.gov + Grants.gov) before the deadline, then submit the application package listed in the official notice.
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